If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small. As always, I encourage you to ask questions.
Is it safe to take Zofran while pregnant?
Taking Zofran while pregnant is low risk, and it has been prescribed for years for pregnancy nausea. That said, Zofran for pregnancy nausea is an off-label use, and there may be better options.
Does Zofran really cause birth defects?
The results of these studies have concluded Zofran causes birth defects, particularly congenital heart defects, cleft palate defects, and kidney defects. The birth defects linked to use of Zofran during pregnancy include: 130% risk of overall birth defects. 620% risk of kidney obstruction birth defects.
What effects does Zofran have on a fetus?
For most of the birth defects studied, researchers found that taking ondansetron during early pregnancy did not appear to increase the chance of having a baby with a birth defect. Women should discuss options for managing nausea and vomiting symptoms during pregnancy with their healthcare providers.
How many times a day can you take Zofran while pregnant?
Ondansetron can be given orally or intravenously in doses up to 8 mg three to four times daily.
What nausea medicine is safe while pregnant?
In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.
Is Zofran safe in second trimester?
A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus.
Does Zofran cross the placenta?
Does Zofran Pass The Placental Barrier To A Significant Degree? Yes. We’ve already covered how Zofran is able to cross the fetal placental barrier, and was found in both human and animal fetal tissue at high concentrations.
Can Zofran cause heart defects in babies?
Now, studies have shown that one of the many birth defects associated with taking Zofran during pregnancy could be a congenital heart defect. This defect has been reported to include babies born with: Atrial Septal Defect (ASD); Ventricular Septal Defect (VSD); and.
Can Zofran cause a miscarriage?
Currently, no scientific evidence has linked the anti-nausea drug Zofran, frequently prescribed “off-label” for morning sickness, to an increased risk of miscarriage.
Is it bad to take Zofran every day?
Ondansetron may be taken up to 3 times a day for 1 to 2 days after your chemotherapy or radiation treatment is finished. If you are taking this medication on a prescribed schedule, take it regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.
How quickly does Zofran work?
Zofran (ondansetron) begins to work within about 30 minutes. It reaches peak blood concentrations in about 2 hours. Zofran’s effects can last 8 to 12 hours. The Zofran dosage varies depending on the severity and cause of the nausea and vomiting.
Does Zofran really help with morning sickness?
Studies suggest that Zofran is the most effective treatment, she said. This medication is typically used to relieve chemotherapy-related vomiting, Fejzo said. Zofran may help control the vomiting from HG, but it doesn’t always help with the nausea, she said.
Is ondansetron safe in first trimester of pregnancy?
A new study from Brigham and Women’s Hospital finds that pregnant women taking the common anti-nausea medication ondansetron during the first trimester have no increased risk of cardiac malformations and only a slight increased risk of oral clefts.
Can you drink water after taking Zofran?
You can take it with, or without, food. If you are prescribed a regular tablet, take it with a full glass of water. If you are prescribed a liquid, measure the dose with a special dose-measuring spoon, not a kitchen spoon. If you are prescribed an “orally disintegrating tablet,” take special precautions.